《SYSUCC鼻咽癌放射治疗手册(英文版)》系统地介绍了鼻咽癌放疗后神经损伤的基础与临床研究的新成果。由于《SYSUCC鼻咽癌放射治疗手册(英文版)》篇幅较多不便于携带,且在基础理论方面涉及较多。为了能够很好地指导临床实践,突出临床实用性,我们特在该书的基础上,结合并补充了近两年国内外在放射性损伤临床诊治方面的新进展,编写了这部以临床应用为主的诊治手册,以期对广大读者能够有所裨益。
Nasopharyngeal carcinoma (NPC) is a cancer prevalent in South China, especially in Guangdong Province. So it is also called the 'Canton Cancer' . Applications of chemotherapy and biological targeted therapy improve control and survival rate of NPC. However, radiation therapy (RT) remains the primary therapeutic method. With the popularization of modern accurate RT techniques, intensity-modulated radiation therapy (IMRT) has been gradually becoming the standard RT technique for NPC. Simultaneously, it brings some problems. For example, more accurate anatomical localization, more precise dosage distribution and stricter protection of normal tissues are required in IMRT. Therefore, there is a pressing need to make a standard for RT now. In Sun Yat-sen University Cancer Center(SYSUCC), research and treatment on NPC has a history of half a century. And the department of Radiation Oncology has conducted IMRT for NPC patients for ten years. Combining our experiences with. relevant guidelines at home and abroad, we wrote this handbook to supply a clinical reference for the radiation oncologists fighting against NPC.
This handbook has the following characteristics:
1 There are systemic introductions of screening, diagnosis, staging, treatment and follow-ups for NPC.
2 Centered on RT of NPC, the latest international definition of cervical lymph nodes, and the latest guidelines of the National Comprehensive Cancer Network (NCCN) have been amalgamated into this manual. Through comparison of different guidelines, we make a summary for delineation of clinical target volumes (CTVs), and anatomical definition and dosage limitation of organs at risk (OARs).
3 This handbook also enrolls some new advices for clinical staging and treatment, which might guide clinical therapy and scientific research.
We hope that this handbook can be of help in standardization of RT for NPC, improvement of international academic exchange, and progression of radiation oncology research. Sincere thanks be to the contributors and the publishers of this handbook!
Part One Screening
Part Two Diagnostic Workup
1 History Taking
2 Laboratory Examination of Hematology
3 imaging Tests
4 Pathologic Classification
Part Three Clinical Staging
1 Common Clinical Stage
2 Prognostic Risk Stratification
3 Neck Lymph Node Levels and Delineation Consensus
4 New Proposal for Clinical Staging of NPC in Age of IMRT.
Part Four Therapeutic Management
1 Principle of Treatment
2 Radiotherapy
3 Chemotherapy
Part Five Follow-up After Treatment
1 Proposal from NCCN Guideline
2 Proposal from EHNS-ESMO-ESTRO Guideline
3 Proposal from SEOM Guideline
4 The Authors' Proposal for Follow-up
Reference